Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with different genetic etiologies. Prospective examination of familial-risk infants informs understanding of developmental trajectories preceding ASD diagnosis, potentially improving early detection.

Objective: To compare outcomes and trajectories associated with varying familial risk for ASD across the first 3 years of life.

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McDonald NM, Senturk D, Scheffler A, Brian JA, Carver LJ, Charman T, Chawarska K, Curtin S, Hertz-Piccioto I, Jones EJH, Klin A, Landa R, Messinger DS, Ozonoff S, Stone WL, Tager-Flusberg H, Webb SJ, Young G, Zwaigenbaum L, Jeste SS. Developmental Trajectories of Infants With Multiplex Family Risk for Autism: A Baby Siblings Research Consortium Study. JAMA Neurol. 2020 Jan 1;77(1):73-81. doi: 10.1001/jamaneurol.2019.3341. PMID: 31589284; PMCID: PMC6784852.