Essentiality and Centrality in Protein Interaction Networks Revisited
Minimum dominating sets (MDSet) of protein interaction networks allow the control of underlying protein interaction networks through their topological placement. While essential proteins are enriched in MDSets, we hypothesize that the statistical properties of biological functions of essential genes are enhanced when we focus on essential MDSet proteins (e-MDSet). Read more “Essentiality and Centrality in Protein Interaction Networks Revisited”