January 2016 – Frost Institute for Data Science & Computing

Screening Tools Identify new Cancer-Inhibiting Compound

Using “big data” sets and powerful computational screening tools, researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have identified a compound that inhibits two different cellular targets in cancer. In a recent study published in Scientific Reports, the researchers described the importance of finding the first-in-class dual inhibitor of the kinase protein EGFR, found in many cancers, and BRD4, a protein that controls the expression of oncogenes, or cancer-promoting proteins. Read more “Screening Tools Identify new Cancer-Inhibiting Compound” →

Publications

Infants Time Their Smiles to Make Their Moms Smile

One of the earliest forms of interaction between mothers and infants is smiling games. While the temporal dynamics of these games have been extensively studied, they are still not well understood. Why do mothers and infants time their smiles the way they do? Read more “Infants Time Their Smiles to Make Their Moms Smile” →

News - Archived

Visualization Goes High-Tech with launch of Viz Lab

An aerial image of a Colombian shantytown appeared on the large display screen with such clarity that the people gathered for the demonstration could identify the types and number of garments hanging from a clothesline on the rooftop of a shack. Demonstrations of the Viz Lab 2D and 3D walls were presented at the Viz Lab Open House on January 14, 2016. Read more “Visualization Goes High-Tech with launch of Viz Lab” →

News - Archived

Cyviz Selected for New Visualization Laboratory

Cyviz, a global leader in high-performance data visualization, collaboration, and command & control systems, announced that it was selected by the University of Miami’s Institute of Data Science and Conputing as the provider of a comprehensive visual display and control solution for the Visualization Lab. Read more “Cyviz Selected for New Visualization Laboratory” →

Lectures & Seminars - Archived

Network Science Seminar, Thursday 1/28/2016

Network science is a mature discipline, and in both systems biology and systems medicine applications, offers a variety of methodological tools useful for integrative inference purposes, elucidating in particular molecular interactions of various type and complexity. An advantage that networks offer refers to representation, interpretation, and visualization properties in systems’ embedded modular configurations. The clusters of genes or proteins that one observes grouped into communities, are reducing de facto the degrees of freedom and reorganizing cellular networks according to a mix of localized characteristics reflecting gene—gene and protein—protein spatio-temporal associative dynamics. Read more “Network Science Seminar, Thursday 1/28/2016” →

Publications

Non-Coding RNAs Profiling in Head and Neck Cancers

The majority of studies on human cancers published to date focus on coding genes. More recently, however, non-coding RNAs (ncRNAs) are gaining growing recognition as important regulatory components. Here we characterise the ncRNA landscape in 442 head and neck squamous cell carcinomas (HNSCs) from the cancer genome atlas (TCGA). Read more “Non-Coding RNAs Profiling in Head and Neck Cancers” →

Publications

Comorbidity Networks: Beyond Disease Correlations

A new paradigm of data-intensive biomedicine is naturally leading to novel inference tools, dealing in particular with complex diseases and comorbidities. Read more “Comorbidity Networks: Beyond Disease Correlations” →

Events - Past

Viz Lab Open House, Thursday 1/14/2016

IDSC invites you to a walk-through tour and demonstration of the new Visualization Laboratory featuring 2D and 3D walls. Join ius anytime between 2:30 and 5:30 PM on Thursday, January 14, 2016, for refreshments and short demonstrations: Read more “Viz Lab Open House, Thursday 1/14/2016” →

Lectures & Seminars - Archived

Systems Biology Data Science Symposium, 1/19-20/2016

Join us for the first Systems Biology Data Science Symposium! The BD2K-LINCS DCIC and the University of Miami will host the two-day Systems Biology Data Science Symposium (SBDSS 2016) on January 19-20, 2016. Click here to add the event to your calendar. Read more “Systems Biology Data Science Symposium, 1/19-20/2016” →

Publications

Regions of Homozygosity Identified by Oligonucleotide SNP Arrays

This study demonstrates that ROHs are much more frequent than previously recognized and often reflect parental relatedness, ascertain autosomal recessive diseases or unravel UPD in many cases. Read more “Regions of Homozygosity Identified by Oligonucleotide SNP Arrays” →

pan>January 2016