![Fig 3. Proteo-genomics analysis of cancer driver events in breast cancer. A) Most differentially expressed proteins in the proteomics signatures constructed by comparing RPPA profiles of Her2E and Luminal A BRC samples; B) Gene expression profile of the genes corresponding to proteins in A) based on RNA-seq data; C) Top 100 CP signatures most connected with the transcriptional signature constructed by comparing RNA-seq profiles of Her2E and Luminal A samples; D) Selected chemical perturbagens and their targets for CP signatures in C).](https://i0.wp.com/idsc.miami.edu/wp-content/uploads/2019/03/F3.medium.gif?resize=440%2C311&ssl=1)
Connecting Omics Signatures of Diseases, Drugs, and Mechanisms of…
iLINCS (http://ilincs.org) is an integrative web-based platform for analysis of omics data and signatures of cellular perturbations. The portal facilitates analysis of user-submitted omics signatures of diseases and cellular perturbations in the context of a large compendium of pre-computed signatures (>200,000), Read more “Connecting Omics Signatures of Diseases, Drugs, and Mechanisms of Actions with iLINCS”