July 2014 – Frost Institute for Data Science & Computing

News

Scientists Meet With Governor on Climate Change Denial

Florida Governor Rick Scott has been repeatedly quoted as saying “I’m not a scientist” when asked whether he believes in man-made climate change. So,10 Florida scientists sent the Governor a letter referring to the “impact of human-induced global warming.” They mentioned a recent government report that found “unambiguous” evidence that human activities—like the burning of fossil fuels—are the cause. Read more “Scientists Meet With Governor on Climate Change Denial” →

Publications

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability…

Depending on endoplasmic reticulum (ER) stress levels, the ER transmembrane multidomain protein IRE1α promotes either adaptation or apoptosis. Unfolded ER proteins cause IRE1α lumenal domain homo-oligomerization, inducing trans autophosphorylation that further drives homo-oligomerization of its cytosolic kinase/endoribonuclease (RNase) domains to activate mRNA splicing of adaptive XBP1 transcription factor. Read more “Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress” →

News - Archived

New Release of the LIFE Search Engine

A new version of the LIFE search engine has been released. LIFE makes it possible to search across data generated at the LINCS project. This new release includes recent data releases from the LINCS Consortium. It has improved search functionality and several new data visualization features. Read more “New Release of the LIFE Search Engine” →

Events - Past

Oak Ridge Leadership Computing Facility Users Meeting

On July 22-24, 2014, Oak Ridge National Laboratory (ORNL) will host a leadership computing users meeting and a tutorial on how to become an OLCF user. The meeting will feature paired talks from OLCF users and code developers who will provide updates on their scientific accomplishments and code achievement, including highlights on their computational requirements for the future. OLCF staff members will discuss ongoing and future initiatives and engage the attendees in how to best provide for and enhance scientific discovery through leadership computing. Read more “Oak Ridge Leadership Computing Facility Users Meeting” →

pan>July 2014

Scientists Meet With Governor on Climate Change Denial

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability…

New Release of the LIFE Search Engine

Oak Ridge Leadership Computing Facility Users Meeting