Publications
By accessing The Cancer Genome Atlas (TCGA) Dr. Capobianco and his team built the wide-spectrum transcriptome landscape of skin cutaneous melanoma (SKCM) from 103 primary tumor samples. They measured the expression levels of protein coding genes and non-coding RNAs (ncRNAs). Read more “Ensemble Modeling Approach Targeting Heterogeneous RNA-Seq Data”
Publications
BRAF protein kinase is a crucial player in melanoma, as it belongs to the highly oncogenic RAS/RAF/MEK/ERK signaling pathway (Matallanas et al., 2011), is mutated in about 50% of melanoma cases (Cantwell-Dorris et al., 2011), is causally linked to melanomagenesis (Dankort et al., 2009) and has recently become a valuable therapeutic target against metastatic melanoma (Menzies and Long, 2014). Read more “Identification of BRAF 3’UTR Isoforms in Melanoma”