Neurons – Frost Institute for Data Science & Computing

The Effect of Jun Dimerization on Neurite Outgrowth and…

Axon regeneration is a necessary step toward functional recovery after spinal cord injury. The AP-1 transcription factor c-Jun has long been known to play an important role in directing the transcriptional response of Dorsal Root Ganglion (DRG) neurons to peripheral axotomy that results in successful axon regeneration. Read more “The Effect of Jun Dimerization on Neurite Outgrowth and Motif Binding” →

Can Chromatin Accessibility be Exploited for Axon Regeneration?

Several studies have demonstrated that the intrinsic ability of neurons to regenerate their axons can be stimulated by maneuvers that favor the open state of chromatin, such as inhibiting histone deacetylase activity or increasing histone acetyltransferase activity. Taken together, these experiments suggest . . . Read more →

n>Neurons

The Effect of Jun Dimerization on Neurite Outgrowth and…

Can Chromatin Accessibility be Exploited for Axon Regeneration?