![Examples of protein quantification via SDS-PAGE. Twenty five micrograms of HeLa cell proteins was loaded along with the proteins recovered from the KI-drug treated cell line A and separated on 10% SDS-PAGE gels. The gel was stained with CBB and the densities of the CBB stain from all lanes are measured. The protein CBB densities in drug-treated samples were compared to that of the HeLa cells, and the protein amounts in each sample was then estimated as described in Supplementary Table 2.](https://i0.wp.com/idsc.miami.edu/wp-content/uploads/2021/03/1-s2.0-S022352341931181X-gr5_lrgExamples-of-Protein-Qualification.jpg?resize=730%2C350&ssl=1)
Protemic Cellular Signatures of Kinase Inhibitor-Induced Cardiotoxicity: Mount Sinai…
Abstract The Drug Toxicity Signature Generation Center (DToxS) at the Icahn School of Medicine at Mount Sinai is one of the centers of the NIH Library of Integrated Network-Based Cellular Signatures (LINCS) program. A key aim of DToxS is to generate both proteomic and transcriptomic signatures that can predict adverse effects, especially cardiotoxicity, of kinase inhibitors approved by the Food and Drug Administration. Read more “Protemic Cellular Signatures of Kinase Inhibitor-Induced Cardiotoxicity: Mount Sinai DToxS LINCS Center Dataset”