Publications
There is a growing list of examples for the existence of the signal‐to‐noise paradox, where in the ensemble‐based climate prediction, the model ensemble mean forecast generally shows higher correlations with observations than with individual ensemble members. Read more “Understanding the Signal-to-Noise Paradox with a Simple Markov Model”
Publications
As more digital resources are produced by the research community, it is becoming increasingly important to harmonize and organize them for synergistic utilization. The findable, accessible, interoperable, and reusable (FAIR) guiding principles have prompted many stakeholders to consider strategies for tackling this challenge. Read more “FAIRshake: Toolkit to Evaluate the FAIRness of Research Digital Resources”
News
University of Miami’s $3.7 million investment in a new supercomputer combined with AT&T’s soon-to-be-installed, campus-wide 5G+ technology will propel the Coral Gables institution forward in solving highly complex problems. With the IBM-built “Triton” supercomputer installed earlier this year, UM can calculate long-term climate predictions for the National Oceanic and Atmospheric Administration (NOAA) weekly instead of monthly. That’s among the 120 to 160 projects the supercomputer is being tapped to calculate. Read more “UM Levels Up South Florida’s Technology Sector”
News
Most musical sounds show strong energy concentrations, such as regular time-frequency patterns of sonic partials, as a sparse energy distribution across the spectrographic analysis plane. Most studies of musical sound are based on strong spectral components such as the energy distribution patterns of the harmonic partials. Read more “The “Dark” Energy Between Sonic Partials: Parametrics Estimation and Analysis of . . .”
Publications
Spectrogram and other time-frequency analysis methods transfer an audio file into an auditory image. When signal processing-based analysis and interpretation is performed on these auditory images instead of an audio signal, spectrographic analyses can identify interesting patterns that focus on Read more “A New Auditory Image for Social Media: Moving Towards Correlation of Spectrographic Analysis . . .”
Publications
Clinical efficacy of targeted signaling inhibitors for hematologic malignancies is limited by outgrowth of subpopulations with alternative pathways independent of the drug target. The eIF4F complex responsible for translation initiation is a convergence point for cancer-promoting signaling pathways and its inhibition leads to decreased expression of key oncoproteins and apoptosis. Read more “Identification of Tractable Drug-Like elF4AI Inhibitors with Potent Anti-Tumor Activity”
Publications
Glioblastoma (GBM) is the most common and malignant adult brain tumor. Despite years of research, few advancements have been made in its management. One promising avenue of research has been treatment with BRD4 inhibitors, which decrease oncogene expression in GBM cells. Read more “Gene 36. Integrating Transcriptomics and Kinomics Identifies Synergistic Drug Combinations for Glioblastoma Treatment”
News
Glioblastoma (GBM) remains the most common adult brain tumor, with poor survival expectations, and no new therapeutic modalities approved in the last decade. Our laboratories have recently demonstrated that the integration of a transcriptional disease signature obtained from Read more “Comp-16. Comprehensive Transcriptomic Analysis of Single Cells From Recurrent and Primary Glioblastoma to Predict Cell-Type-Specific Therapeutics”
News
The University of Miami recently signed an agreement with AT&T to become the company’s first college campus to adopt 5G+ and Multi-access Edge Compute (MEC) technology. The term 5G refers to a larger cellular bandwidth that will deliver more data from the internet to wireless devices at a faster pace. This would help large data files like videos and graphics load quicker on phones and tablets, said Nick Tsinoremas, IDSC Institute Director. Read more “UM will be first to Adopt AT&T 5G+ Edge Technology”