Publications
Identification of DOT1L Inhibitors by Structure-Based Virtual Screening Adapted…
Within cells, DNA is condensed into chromatin by histone proteins. Covalent post-translational modifications of histones such as methylation, acetylation, and ubiquitination of basic histone residues regulate the accessibility of gene loci activating or repressing their transcription. Read more “Identification of DOT1L Inhibitors by Structure-Based Virtual Screening Adapted from a Nucleoside-Focused Library”